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Behmanesh F, Pasha H, Sefidgar S A A, Moghadamnia A, Basirat Z. A comparative study of antifungal activity of Lavender brew, Lavender essential Oil, and Clotrimazole: an in vitro study. Caspian J Reprod Med 2015; 1 (1) :25-29
URL: http://caspjrm.ir/article-1-46-en.html

Methods: The fungus cell count was done through Thoma counting chambers and Hemocytometer slide. Having prepared the dilution (6 × 106 of standard Candida albicans, S.C.a-PTCC-2657) in the Sabouraud Agar liquid medium, the essential oil and brew of Lavandula angustifolia and Clotrimazole were added to different dilutions (½ , ¼ , ⅛) (in 4 stages) before the fungus cell count was done. Having obtained the necessary information, the data were analyzed through Statistical Package for the Social Sciences (SPSS), and a general linear model was used for the analysis of the data. The test results were then compared. 

Results: The number of fungi cells in Lavender brew (14 × 106) and Lavender essential oil (35× 106) decreased significantly compared with those of Clotrimazole (93 × 106) and fungus control (188 × 106) (p<0.01). Also, the fungus cell count in dilutions of ½ and ¼ of the drugs in the brew, and in dilutions of ⅛ in essential oil were less than those of other proportions. The highest antifungal efficacies of the drugs were observed in higher dilution (p< 0.01), and Clotrimazole had the least antifungal effect.

Conclusion: Lavender brew and Lavender essential oil had more antifungal effect on the standard Candida albicans when compared with Clotrimazole.