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Showing 2 results for Moghadamnia
Fereshteh Behmanesh, Hajar Pasha, Seyyed Ali Asghar Sefidgar, Aliakbar Moghadamnia, Zahra Basirat,
Volume 1, Issue 1 (Caspian J Reprod Med 2015)
Abstract
Introduction: Vaginal yeast infections (candidiasis) are among the most common gynecologic infections in women. Due to the high prevalence of vaginal candidiasis and its recurrence, followed by such chemical treatment as Clotrimazole, this study was performed with the broad aim of comparing the in vitro effects of Lavender brew, Lavender essential oil, and Clotrimazole on the growth of the standard strains of Candida albicans.
Methods: The fungus cell count was done through Thoma counting chambers and Hemocytometer slide. Having prepared the dilution (6 × 106 of standard Candida albicans, S.C.a-PTCC-2657) in the Sabouraud Agar liquid medium, the essential oil and brew of Lavandula angustifolia and Clotrimazole were added to different dilutions (½ , ¼ , ⅛) (in 4 stages) before the fungus cell count was done. Having obtained the necessary information, the data were analyzed through Statistical Package for the Social Sciences (SPSS), and a general linear model was used for the analysis of the data. The test results were then compared.
Results: The number of fungi cells in Lavender brew (14 × 106) and Lavender essential oil (35× 106) decreased significantly compared with those of Clotrimazole (93 × 106) and fungus control (188 × 106) (p<0.01). Also, the fungus cell count in dilutions of ½ and ¼ of the drugs in the brew, and in dilutions of ⅛ in essential oil were less than those of other proportions. The highest antifungal efficacies of the drugs were observed in higher dilution (p< 0.01), and Clotrimazole had the least antifungal effect.
Conclusion: Lavender brew and Lavender essential oil had more antifungal effect on the standard Candida albicans when compared with Clotrimazole.
Syed Gholam Ali Joursarai, Sima Shahabi, Ali Akbar Moghadamnia, Ebrahim Zabihi, Ghorban Maliji, Tahereh Abbasi, Soghra Ahmadzadeh, Ali-Asghar Younesi, Mohsen Esmaili, Fereshteh Pour Abdolhossein,
Volume 2, Issue 2 (Caspian J Reprod Med 2016)
Abstract
Background: According to a popular Iranian belief, Camphor can not only suppress libido but also decrease the function of the reproductive system. In this regard, this study was conducted to evaluate the role of Camphor in the number of embryos in mice.
Methods: In this study, 40 male and 80 female albino mice, weighing 30-35 g, were randomly divided into 8 groups, including a control group, a sham group that received the vehicle only (olive oil), and six experimental groups that received Camphor. Three experimental groups received camphor by p.o. (gavage) and the other three experimental groups received camphor by i.p. (intraperitioneal) in doses of 10, 20, and 40 mg/kg for 15 days. Mating was confirmed after coupling a male with a female mouse. Vaginal plaque was also considered for mating. Embryos were examined during the period of gestation.
Results: The mean number of embryos in control, sham, and received Camphor (10, 20, and 40 mg/Kg) by o. p. were 9.7 ± 4.6, 7.3 ± 4.3, 9.9 ±4.7, 8.6 ± 5.2, and 8.3 ±4.8, respectively. The mean number of embryo in received Camphor (10, 20, and 40 mg/Kg) by i. p. were 7.6 ± 5.4, 8.3 ± 3.4, and 7.3 ± 6.2, respectively. There were no significant differences in the number of embryos between control, sham, and experimental groups in both groups.
Conclusion: Further investigations with more focus on the effect of Camphor on sexual behavior in mice need to be carried out.
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