دوره 1، شماره 2 - ( 3-1394 )
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Abedi Samakoosh M, Yazdani S, Bouzari Z, Golsorkhtabaramiri M. Maternal serum C - reactive protein and fibrinogen concentration in women with pre-eclampsia. Caspian J Reprod Med 2015; 1 (2) :9-12
URL: http://caspjrm.ir/article-1-56-fa.html
URL: http://caspjrm.ir/article-1-56-fa.html
Maternal serum C - reactive protein and fibrinogen concentration in women with pre-eclampsia. نشریه طب تولید مثل خزر. 1394; 1 (2) :9-12
: (12821 مشاهده)
Background: Despite many studies published in recent years concerning pathogenic mechanisms of pre-eclampsia, but this issue remains controversial. The aim of the present study was to compare C-reactive protein (CRP) level and fibrinogen concentration obtained from pregnant women with pre-eclampsia with those obtained from women with normal pregnancies.
Methods: In a case-control study, 40 pregnant women with mild pre-eclampsia were studied. The maternal serum CRP and fibrinogen concentration of the 40 patients were compared with 55 pregnant women with non-preeclampsia as a control group. CRP was examined using quantitive nephlometry and fibrinogen concentration was measured by clotting system. An independent sample t-test was used for analysis.
Results: Maternal serum CRP was higher in women pregnant with pre-eclampsia compared with those from pregnant women normal pregnancies (p= 0.01). The independent t-test did not reveal any statistically significant differences in the fibrinogen concentration between these pregnant women, either with or without pre-eclampsia.
Conclusion: The findings of this study indicated that a novel increased CRP was identified among pregnant women with pre-eclampsia, making inflammatory marker as a promising new approach for the detection of pre-eclampsia.
نوع مطالعه: پژوهشي |
موضوع مقاله:
Obstetrics and Gynecology
دریافت: 1394/1/17 | پذیرش: 1394/4/3 | انتشار: 1394/4/8
دریافت: 1394/1/17 | پذیرش: 1394/4/3 | انتشار: 1394/4/8
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