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Doppler flow parameters of fetal middle cerebral artery in gestational diabetes: a comparative analysis with normal pregnancy and correlation with pregnancy outcome
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: (406 مشاهده) |
Background: The objectives of this study were to compare Doppler flow parameters of the fetal middle cerebral artery in pregnancy with gestational diabetes versus normal pregnancy, and to study the correlation of Doppler flow parameters of fetal middle cerebral artery (MCA) with pregnancy outcome in gestational diabetes mellitus.
Methods: All pregnant women attending antenatal care (ANC) up to 34 weeks with oral glucose tolerance test (OGTT) ≥ 140mg/dl were defined as cases, and those with OGTT < 140 mg/dl were taken as controls. All patients underwent Doppler ultrasound after 34 completed weeks, and Doppler flow parameters [Pulsatility Index (PI), Resistance Index (RI), peak systolic velocity (PSV), and Systolic Diastolic (S/D) ratio] were noted. Pregnancy outcomes among were noted.
Results: MCA PI and MCA PSV showed a statistically significant difference between both groups with p= 0.0234 and P <0.001, respectively. MCA PI was significantly higher in cases compared to controls, whereas MCA PSV was significantly lower in cases than in controls. MCA RI values were higher in cases. In addition, MCA S/D ratio values were lower in controls compared to cases.
Fetal MCA PI on Doppler velocimetry were significantly higher in the GDM group, and MCA PSV was significantly lower in the study group, MCA RI and MCA S/D ratio were not significantly different. Maternal complications were found to be more frequent in GDM compared to non-GDM. MCA PSV was significantly associated with development of PIH in GDM. The rate of NICU admission, RDS, & hypoglycemia were significantly higher in babies of GDM mothers.
Conclusion: Our findings suggest a potential role for Doppler assessment of MCA in predicting adverse outcomes in GDM pregnancies. Therefore, we recommend that antenatal assessments of gestational diabetic pregnancies should include Doppler parameters in the third trimester. |
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نوع مطالعه: پژوهشي |
موضوع مقاله:
Reproductive Health
دریافت: 1402/11/1 | پذیرش: 1403/3/13 | انتشار: 1403/4/2
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