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Endometrial pathologies in abnormal uterine bleeding: prevalence, patterns, and perspectives: A cross sectional study
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: (1373 مشاهده) |
Background: Abnormal uterine bleeding (AUB) is a common gynecological challenge, stemming from various endometrial pathologies. This study aims to assess their prevalence, age distribution, symptomatology correlation, and compare sampling techniques.
Methods: This prospective cross-sectional study was conducted at a single teaching institute, involving 150 female participants aged between 18 and 70 years who presented with AUB. Endometrial samples were collected using one of three methods: OPD Pipelle brush, surgical dilatation and curettage (D&C), or hysteroscopy.
Results: The study found 41-50-year-olds most affected by AUB (40%), with 64% having given birth three or more times. Proliferative and secretory changes were common (35.3% and 16% respectively). Endometrial hyperplasia without atypia occurred in 12% and with atypia in 4.7%. Endometrial carcinoma was in 3.3% and polyps in 5.3% of cases. Heavy menstrual bleeding with normal duration affected 64%. Technical challenges included sampling failure in 2 pipelle biopsies and 7 D&C cases. Inadequate samples were obtained in 2 pipelle biopsy and 5 D&C cases. Uterine perforation occurred once, managed conservatively.
Conclusion: Our study underscores the burden of endometrial pathologies in AUB patients with predominant proliferative and secretory changes. Sampling challenges, particularly with pipelle biopsy and D&C, emphasize the need for refining methods and exploring alternatives like transvaginal sonography and hysteroscopy to enhance diagnostic accuracy and patient outcomes in AUB management. |
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نوع مطالعه: پژوهشي |
موضوع مقاله:
Obstetrics and Gynecology
دریافت: 1402/12/7 | پذیرش: 1403/2/13 | انتشار: 1403/2/22
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