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Showing 7 results for Fertility

Seddigheh Esmaeilzadeh, Mouloud Agajani Delavar, Nargess Gholizadeh Pasha,
Volume 1, Issue 1 (2-2015)
Abstract

Background: The treatment of infertility and the quality of life in women is now considered equally important. The aim of the study was to determine the quality of life (QoL) of married women aged 20-45 years and to compare QoL domain in fertile and infertile women. 

Methods: In a community based study, the Wellness and Quality of Life Questionnaire (WHOQOL) was used to assess the QoL of married women. A total of 1,140 women with the age range of 20-45 were selected using standard cluster sampling technique in Babol, Iran. Among those women who attempted conception, 168 of the women experienced difficulty conceiving at some stage in their lives. Then, the QoL of the women who had experienced infertility were compared with those of other fertile women. The questionnaire containing 55 items comprised five domains: physical state, mental/emotional state, stress evaluation, life enjoyment, and overall quality of life. Lower scores in three domains: physical state, mental/emotional state, and stress evaluation mean better QoL. Higher scores in life enjoyment and overall quality of life mean better QoL. 
Results: The means of the QoL of married women in physical status, mental/emotional state, stress evaluation, life enjoyment, and overall QoL were 19.0±5.3, 20.0±6.8, 23.4±7.8, 32.6±5.3, and 61.5±10.1, respectively. There was no significant relationship in the mean scores in the five domains of QoL between the fertile and infertile groups. Logistic regression also indicated that infertility was associated with higher (worse) scores in the mental/emotional state domain (p=0.018), and fertility was associated with higher scores (better) in overall score QoL (p=0.003). 
Conclusion: The results can be regarded as useful findings to make more efficient interventions for infertile women.

Afsaneh Bakhtiari , Zahra Basirat, Mohammad-Reza Aghajani Mir,
Volume 1, Issue 3 (10-2015)
Abstract

Introduction: Infertility is a major stressor in life and can cause disturbances in both sexual and marital relationships. Therefore, the objective of this study was to determine the frequency of sexual dysfunctions among infertile couples, who referred to the infertility center in Babol, Iran, and the identification of the factors associated with these problems.

Method: A cross-sectional study was performed on 236 partners of infertile couples. A standard questionnaire named international classification DSM-IV was used to assess the frequency and the type of sexual dysfunction. The data were analyzed by descriptive statistics and adjusted odds ratios with their 95% CIs.

Results: According to the results, around 58% of men were found to suffer from sexual dysfunction. The most prevalent type of sexual dysfunction was premature ejaculation, (34.7%), orgasm disorder (28.0%), desire sexual disorder (9.2%), delayed ejaculation (8.5%), retrograde ejaculation (6.8%) and erection dysfunction (5.5%). The men with a history of primary infertility had 3.61 fold risk of sexual dysfunction compared to women who had secondary infertility. Male Infertility (odds ratio, 3.61 95% CI, 2.13-4.58) and idiopathic were (odds ratio, 3.43 1.23-4.85) factors significantly associated with sexual dysfunction. There was 4.92 fold risk of sexual dysfunction observed in men whose wives had sexual dysfunction as compared with those whose wives had no sexual dysfunction.

Conclusion: This study shows a high prevalence of sexual dysfunction for male partners of infertile couples in a community in Babol, Iran. It would be beneficial to establish a sexual clinic in infertility centers for the professional staff to monitor infertile couples.


Syed Gholam Ali Joursarai, Sima Shahabi, Ali Akbar Moghadamnia, Ebrahim Zabihi, Ghorban Maliji, Tahereh Abbasi, Soghra Ahmadzadeh, Ali-Asghar Younesi, Mohsen Esmaili, Fereshteh Pour Abdolhossein,
Volume 2, Issue 2 (12-2016)
Abstract

Background: According to a popular Iranian belief, Camphor can not only suppress libido but also decrease the function of the reproductive system. In this regard, this study was conducted to evaluate the role of Camphor in the number of embryos in mice.

Methods: In this study, 40 male and 80 female albino mice, weighing 30-35 g, were randomly divided into 8 groups, including a control group, a sham group that received the vehicle only (olive oil), and six experimental groups that received Camphor. Three experimental groups received camphor by p.o. (gavage) and the other three experimental groups received camphor by i.p. (intraperitioneal) in doses of 10, 20, and 40 mg/kg for 15 days. Mating was confirmed after coupling a male with a female mouse. Vaginal plaque was also considered for mating. Embryos were examined during the period of gestation.

Results: The mean number of embryos in control, sham, and received Camphor (10, 20, and 40 mg/Kg) by o. p. were 9.7 ± 4.6, 7.3 ± 4.3, 9.9 ±4.7, 8.6 ± 5.2, and 8.3 ±4.8, respectively. The mean number of embryo in received Camphor (10, 20, and 40 mg/Kg) by i. p. were 7.6 ± 5.4, 8.3 ± 3.4, and 7.3 ± 6.2, respectively. There were no significant differences in the number of embryos between control, sham, and experimental groups in both groups.

Conclusion: Further investigations with more focus on the effect of Camphor on sexual behavior in mice need to be carried out.


Ali Shalizar Jalali,
Volume 3, Issue 1 (4-2017)
Abstract

Iatrogenic vas deferens injuries (IVDIs) as inadvertently medical conditions are critical complications of surgical operations in the inguinal region of children and adults. It is well documented that any scant disturbance in vas deferens tunica muscularis or mucosa will endanger fertility and unintentionally manipulations during inguinal hernia repair can cause perforation and/or obstruction of damaged vas deferens resulting in male fertility reduction. It has also been suggested that IVDIs can play crucial roles in formation of anti-sperm autoantibodies and sympathetic vasospasm leading to bilateral testicular deterioration as well as sperm motility and capacitation impairments. In line with that, it seems that non-recognized IVDIs may have destructive effects on spermatogenesis resulting in fertility problems and careful attention to surgical detail should be considered during inguinal region surgical procedures to prevent IVDIs. However, recent progresses in urological microsurgeries and assisted reproductive technologies provide remarkable improvements in fertility outcomes of patients even with serious iatrogenic reduction in fertility.


Farzaneh Montazerifar, Marzieh Ghasemi, Nafiseh Arabpour, Mansour Karajibani, Narjes Keikhah,
Volume 6, Issue 1 (5-2020)
Abstract

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of fertility age. The aim of this study was to compare the prevalence of metabolic syndrome (MetS) in women with and without PCOS, who referred to infertility clinic.
Methods: In this case control study, 120 women with PCOS and 120 healthy controls, who had referred to infertility clinic, were selected for the purpose of this study. Polycystic ovarian disease was diagnosed according to the Rotterdam (2003) criteria, and the prevalence of MetS was assessed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria for both groups.
Results: Women with PCOS had markedly higher prevalence of the MetS than healthy controls (29.2% and 7.5%, respectively; P<0.0001). Among risk factors of MetS, the most prevalent components were low level of HDL cholesterol (97.5%), central obesity (86.7%), and high triglyceride (77.5%). The prevalence of MetS increased with age and BMI (P<0.0001).
Conclusion: The results suggest that the MetS was more frequent in PCOs infertile women, especially in upper age groups. Thus, the screening of these patients is suggested for preventive strategies in high risk individuals.
Elias Kargar-Abargouei, Esmaeel Ghani , Hamzeh Badeli-Sarkala, Mohammad Zamani Rarani , Zeinolabedin Sharifian Dastjerdi, Sakine Arab Firouzjaei, Maryam Arab Firouzjaei,
Volume 7, Issue 1 (6-2021)
Abstract

Background: Since the emergence of the pandemic of coronavirus disease (COVID-19) through severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019, we still have little knowledge about the mechanisms of pathogenesis of COVID-19. Surprisingly, early studies reported that men are more susceptible to COVID-19 compared to women. These findings raise the question of whether COVID-19 infection can negatively affect male fertility. Since angiotensin-converting enzyme-2 (ACE2) receptor, known as the entrance rout of virus into human cells abundantly on testicular cells, it is hypothesized that the virus can also have devastating effects male fertility.
Methods: The present study was conducted a narrative review of the literature on male infertility and COVID-19. We searched PubMed, Scopus, and Google scholar for papers. Full-text journal articles between the years 2019 and 2020 were reviewed for relevant articles.
Results: There is emerging finding, which provides support for the susceptibility of male reproduction health to COVID-19 infection. In the current review article, we documented an overview of male reproductive function manifestations and the possible male infertility mechanisms of COVID-19 infection. Certainly, clarifying the mechanism of these findings will lead to the timely management and treatment of infected patients.
Conclusion: This review suggests that male counseling about their fertility and the evaluation of their reproductive system function should be performed. 
John Jude Annan , Mike Addison, Anthony Enimil, Robert Aryee, Augustine Twumasi , Fati Ibrahim ,
Volume 9, Issue 2 (12-2023)
Abstract

Background: Male factor infertility, often characterized by deficiencies in sperm count, motility, and morphology, is a significant concern in the context of infertility. Azoospermia, the absence of spermatozoa in the ejaculate, represents a particularly challenging condition. This study aimed to investigate the prevalence of azoospermia among male partners of couples undergoing infertility treatment at a fertility center in Ghana.
Methods: A six-year retrospective descriptive investigation was conducted, focusing on male partners of couples seeking infertility treatment at the Emena Diagnostic and Fertility Centre. Semen analysis results indicative of azoospermia were systematically retrieved and analyzed. All samples were collected through masturbation and adhered to the stringent criteria outlined by the World Health Organization (WHO).
Results: Among 1,224 semen analyses conducted between 2015 and 2020, 67 cases of azoospermia were identified, accounting for approximately 5.5% of the total cases. Participants' ages ranged from 28 to 69 years, with a mean age of 41.0 (SD = 9.2) years. The majority of azoospermic individuals belonged to the 30–39 age group (44.8%), followed closely by the 40–49 age group (31.3%). Notably, 90% of the cases fell within the age range of 30–59 years. Analysis of semen characteristics revealed variations in viscosity and volume, with hypospermia most prevalent in the 40–49 age group.
Conclusion: This study provides valuable insights into the prevalence and characteristics of azoospermia among male partners seeking infertility treatment in Ghana. These findings contribute to a better understanding of male infertility and can inform strategies for its management and treatment in clinical settings.
 

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Caspian Journal of Reproductive Medicine
Caspian J Repord Med: Infertility and Reproductive Health Research Center of Babol University of Medical Sciences, Babol-Amol old highway, after Mohammadhasan Khan bridge, Babol, Mazandaran, Iran, P.O. Box: 47135-547 Tel: +98-11-32274881-2 Fax: +98-11-32274880 E-mail: info@caspjrm.ir Website: www.caspjrm.ir
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