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:: Volume 1, Issue 2 (Caspian J Reprod Med 2015) ::
Caspian J Reprod Med 2015, 1(2): 10-13 Back to browse issues page
Maternal serum C - reactive protein and fibrinogen concentration in women with pre-eclampsia
Mohammad Abedi Samakoosh , Shahla Yazdani * , Zinatosadat Bouzari , Masoumeh Golsorkhtabaramiri
Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran
Abstract:   (3046 Views)

Background: Despite many studies published in recent years concerning pathogenic mechanisms of pre-eclampsia, but this issue remains controversial. The aim of the present study was to compare C-reactive protein (CRP) level and fibrinogen concentration obtained from pregnant women with pre-eclampsia with those obtained from women with normal pregnancies. 

Methods: In a case-control study, 40 pregnant women with mild pre-eclampsia were studied. The maternal serum CRP and fibrinogen concentration of the 40 patients were compared with 55 pregnant women with non-preeclampsia as a control group. CRP was examined using quantitive nephlometry and fibrinogen concentration was measured by clotting system. An independent sample t-test was used for analysis. 
Results: Maternal serum CRP was higher in women pregnant with pre-eclampsia compared with those from pregnant women normal pregnancies (p= 0.01). The independent t-test did not reveal any statistically significant differences in the fibrinogen concentration between these pregnant women, either with or without pre-eclampsia. 
Conclusion: The findings of this study indicated that a novel increased CRP was identified among pregnant women with pre-eclampsia, making inflammatory marker as a promising new approach for the detection of pre-eclampsia.
Keywords: CRP analysis, Female, Fibrinogen, Inflammatory marker, Pregnancy Complications
Full-Text [PDF 176 kb]   (933 Downloads)    
Type of Study: Original Research | Subject: Obstetrics and Gynecology
Received: 2015/04/6 | Accepted: 2015/06/24 | Published: 2015/06/29
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Abedi Samakoosh M, Yazdani S, Bouzari Z, Golsorkhtabaramiri M. Maternal serum C - reactive protein and fibrinogen concentration in women with pre-eclampsia. Caspian J Reprod Med. 2015; 1 (2) :10-13
URL: http://caspjrm.ir/article-1-56-en.html


Volume 1, Issue 2 (Caspian J Reprod Med 2015) Back to browse issues page
Caspian Journal of Reproductive Medicine
Caspian J Repord Med: Infertility and Reproductive Health Research Center of Babol University of Medical Sciences, Babol-Amol old highway, after Mohammadhasan Khan bridge, Babol, Mazandaran, Iran, P.O. Box: 47135-547 Tel: +98-11-32274881-2 Fax: +98-11-32274880 E-mail: info@caspjrm.ir Website: www.caspjrm.ir
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